A Handbook of Experiments in Pre - clinical Pharmacology - Motilal Banarsidass #author

A Handbook of Experiments in Pre-clinical Pharmacology

Author(s): Sanjay Kasture
Publisher: Career Publications
Language: English
Total Pages: 110
Available in: Paperback
Regular price Rs. 150.00
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Description

A Handbook of Experiments in Pre-clinical Pharmacology" is a comprehensive guide that provides practical knowledge and detailed procedures related to pre-clinical pharmacology experiments. It is commonly used by students, researchers, and professionals in the field of pharmacology to understand the fundamental concepts and techniques involved in testing and evaluating drug candidates before clinical trials.

Typically, such handbooks include:

  1. Introduction to Pre-clinical Pharmacology: An overview of the stages of drug development, from discovery through animal testing, before moving to human clinical trials.

  2. Animal Models: Information on various animal models (rats, mice, rabbits, etc.) used in pharmacological studies to simulate human diseases and conditions.

  3. Pharmacokinetic Studies: Methods to study the absorption, distribution, metabolism, and excretion (ADME) of drugs in animals.

  4. Pharmacodynamic Studies: Techniques to evaluate the effects of a drug on a biological system, including dose-response relationships and mechanism of action.

  5. Safety and Toxicity Studies: Guidelines for conducting tests to assess the safety of a drug, such as acute and chronic toxicity studies, genotoxicity, and reproductive toxicity studies.

  6. Behavioral and Biochemical Assays: Various tests used to assess the effects of drugs on the nervous system and other organ systems, as well as biochemical markers.

  7. Statistical Analysis: Approaches to analyzing data from pre-clinical studies to determine the efficacy and safety of drugs.

  8. Ethical Considerations: Ethical issues and guidelines related to the use of animals in research.